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In 1994, Pfizer scientists discovered that sildenafil, which also inhibits the PDE5 enzyme, caused penile erection in males participating in a clinical study of a heart medicine. Although ICOS scientists were not testing compound IC351 for treating ED, they recognized its potential usefulness for treating that disorder. Soon, in 1994, ICOS received a patent for compound IC351 (structurally unlike sildenafil and vardenafil), and Phase 1 clinical trials began in 1995.
Subsequently, the FDA approved both vardenafil[27] and tadalafil in 2003. For details about tadalafil’s recommended dosages, see the "Tadalafil dosage" section above. To help make sure you don’t miss a dose, try using a medication reminder. This can include setting an alarm or putting a note where you’ll see it, such as on your bathroom mirror or bedside table.
While using this medication, some may notice increased sexual confidence as they can enjoy intimacy without the interruptions of erectile difficulties. However, it’s essential to be cautious, as it may lead to a potential drop in energy levels afterward. If you’re taking tadalafil as needed for erectile dysfunction, talk with your doctor about the timing of your dose. You may be able to have sexual activity after 30 minutes and up to 36 hours after taking your tadalafil dose. Ordering Brand Cialis | Tadalafil from our online pharmacy is easy. All you need to do is select the required dosage and quantity of pills above.
How to take tadalafil
Your doctor will ultimately prescribe the smallest dosage that provides the desired effect. This long-lasting effect is the distinct difference between Viagra and Cialis, and the reason why men will select Cialis over the other PDE5 inhibitor drugs available. Always consult your doctor before combining it with other medications to avoid potential interactions.
In line with MHRA guidelines, importing Brand Cialis for BUY XANAX WITHOUT PRESCRITION personal use is allowed, provided the quantity is within approved limits and accompanied by a valid prescription, which we can help facilitate. This opens up cost-efficient options, including high-quality generic alternatives. Purchasing Brand Cialis via our online pharmacy is straightforward and secure. Your prescription will be processed promptly, and all imports meet the legal requirements set by UK. This ensures you have budget-friendly and convenient access to your medication.
Impact on Daily Life
Brand Cialis typically begins to work within 30 minutes, but individual response times may vary. While there are no strict dietary limits, avoid excessive alcohol consumption, which can negatively affect your results.

The FDA has also approved tadalafil for the treatment of both benign prostatic hyperplasia and erectile dysfunction where the two conditions co-exist. Tadalafil, the key component in Brand Cialis, is a phosphodiesterase type 5 (PDE5) inhibitor. It enhances the effects of nitric oxide, a natural chemical the body releases during sexual stimulation.
Brand Cialis, containing the active ingredient Tadalafil, is a medication designed for the treatment of erectile dysfunction (ED) in men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual stimulation. Approved and regulated by the UK's Medicines and Healthcare products Regulatory Agency (MHRA), Brand Cialis is a trusted option for those struggling with ED. Cialis works by relaxing the muscles around the penis, promoting blood flow in the area. This allows the penis to fill with blood easier, making it significantly easier for men to gain and maintain an erection.